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ANIDULAFUNGIN

1. Product introduction

 

  Anidulafungin is an echinocandin antifungal drug, similar products are micafungin, caspofungin, used for the treatment of esophageal candidiasis, candida bacteremia and other types of Candida infections, including peritonitis and abdominal abscess. Studies have confirmed that it has Chemicalbook has a strong ex vivo and in vivo antifungal activity, and does not have cross-resistance. Fenpropathin antifungal antibiotics have become an important drug in the clinical treatment of systemic fungal infections, and this class of drugs has the advantages of high antimicrobial activity and low adverse reactions. Studies presented at the 2005 ICAAC meeting have shown that anifungin is used in comparison with fluconazole for the treatment of candidemia and invasive candidiasis.

 

2. Technology parameter

 

  Fermentation (ECB) + Bioconversion (ECBN) + DSP+ Synthesis process; 
  ECB Fermentation titre: 1-1.5g/L; 
  Fermentation time: 260±24hrs