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6-aminopenicillanic acid(6-APA)

1. Product introduction

 

  6-Aminopenicillanic acid is an important precursor for the synthesis of β-lactam antibiotics and is the main product of the hydrolysis of penicillin G (PenG) by penicillin acyltransferase (PA). It has a small inhibitory capacity and can be introduced into different side chains to obtain a variety of penicillins with different potencies. It is an important intermediate for the production of the semi-compound antipenicillin antibiotics ampicillin sodium and amoxicillin. 

 

2. Technology 

 

  Enzymatic process